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The VersaFoam Advantage
Optimizes delivery
Patient preference
Compliance
Suitable for multiple body areas
Easy to apply
Scientific Data
Bibliography
 
References:

1 Huang X, Tanojo H, Lenn J, Deng CH, Krochmal, L. VersaFoam: A Novel Vehicle for the Delivery of Topical Corticosteroids. J Am Acad Dermatology: 2005;53:S26-38. (see page S31-Figure 6)

2 Tanojo et al. American Academy of Dermatology Annual Meeting 2004; Poster 668.

3 Data on file, Stiefel Laboratories
 
 

Optimizes delivery of active ingredients.1

Clinical significance of in vitro data is unknown

VERSAFOAM-HF™

Impact of vehicle on clobetasol propionate skin permeation and drug distribution in vitro
Cumulative amount of clobetasol propionate (CP) after topical application of CP in five different vehicles.

Amount in Skin Layers at 24h in vitro1
Skin distribution profile of clobetasol propionate (CP) 24 hours after topical application of CP in five different vehicles.

graph
The results from this study demonstrate that foam is an efficient drug delivery vehicle for permeation and distribution of clobetasol proprionate in comparison to solution, lotion or creams.

In vitro Skin Permeation of Clindamycin Phosphate Formulations2
Penetration of clindamycin from VERSAFOAM-HF versus a gel formulation.

graph

VERSAFOAM-EF™
In vitro Skin Penetrations of Clobetasol Propionate Formulations3
Delivery of clobetasol propionate from VERSAFOAM-EF (EF Foam) versus spray and emollient cream formulations, and equivalent to lotion formulation.

graph